About 8 results found for searched term "PIM-1 Inhibitor 2" (0.256 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7140 | PIM-1 Inhibitor 2 | Others |
| PIM-1 Inhibitor 2 is a pim-1 kinase inhibitor. | ||
| M2321 | 17-DMAG (Alvespimycin) hydrochloride | HSP |
| Alvespimycin, NSC 707545 | ||
| 17-DMAG (Alvespimycin, KOS-1022, NSC 707545) hydrochloride is a potent HSP90 inhibitor with IC50 of 62 nM. | ||
| M2945 | Pimozide | Dopamine Receptor |
| R6238 | ||
| Pimozide is an antagonist of 6-hydroxyapatide against 6-hydroxyapatide, with Ki values of 1.4 nM, 2.5 nM and 588 nM for 6-hydroxyapatide, D3 and D1 receptors, respectively. Pimozide also has a high affinity for α1-adrenoceptor. Ki value is 39 nM. Pimozide is also an inhibitor of STAT3 and STAT5, and piperimidate triggers ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1. | ||
| M3745 | TCS PIM-1 1 | Pim |
| SC 204330 | ||
| TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s > 20,000 nM). | ||
| M8921 | Bentamapimod | JNK |
| AS-602801 | ||
| Bentamapimod, also known as AS602801, is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. | ||
| M10227 | Pim1/AKK1-IN-1 | Pim |
| LKB1/AAK1 dual inhibitor | ||
| Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively. | ||
| M30126 | Alvespimycin | HSP |
| 17-DMAG; NSC 707545 | ||
| Alvespimycin (17-DMAG) is a potent inhibitor of Hsp90, binding to Hsp90 with an EC50 of 62 ± 29 nM. | ||
| M45300 | CK2/PIM1-IN-1 | Casein Kinase |
| CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1 with IC50 values of 3.787 μM and 4.327 μM for the effects of CK2 and PIM1, respectively.CAS 번호410483-84-5 | ||
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